BPC-157
aka Body Protection Compound 157, PL14736
A short chain of amino acids first found in your stomach's natural protective fluid.
Technically · Synthetic peptide (gastric protein fragment)
In one sentence
A fragment from your stomach lining that's become the go-to recovery peptide for tendon, ligament, and gut injuries.
— Like wound-healing on demand — the body uses it naturally, and the synthetic version is a focused dose.
Half-life
~30 minutes (parenteral)
Burns off fast — about 30 minutes after injection (so you re-dose daily).
Dosing
1–2× daily
How often you take a dose
Route
SubQ · Oral
How it goes into the body
Status
Research
Sold for lab research — not approved for humans
What it is
Scientists found this 15-amino-acid chain in human gastric juice — the natural goop that protects your stomach. The synthetic version is studied for healing tendons, ligaments, and gut tissue. Heads up: all the strong evidence is in animals, not humans yet.
The full technical answer
A 15-amino-acid sequence derived from a protein in human gastric juice. Studied for tendon, ligament, and gut healing. No human RCTs published — all trial data is animal model.
How it works
It seems to do three useful things: grow new blood vessels to injury sites (so repair crews can get there), turn down inflammation, and speed up wound healing in tendons and gut tissue. The how is still being worked out, but the animal results are consistent.
The full technical answer
Animal studies suggest it promotes angiogenesis (new blood vessel growth), modulates the nitric oxide system, and accelerates wound healing in tendon and gut tissue.
What the research says
Robust animal data on tendon repair, gut ulcer healing, and angiogenesis. Zero published human RCTs — all human use is anecdotal.
Sources: PubMed: BPC-157 reviews
Common dosing ranges
- Range
- Animal studies: 10 mcg/kg. Human protocols typically 250–500 mcg/day (no clinical validation).
- Frequency
- 1–2× daily
- Duration
- Most protocols cycle 4–8 weeks on, then break
Sources: PubMed reviews
How to take it
Practical guidance synthesized from clinical protocols, FDA labels, and clinician interviews. Always cross-check with a prescribing physician.
Best time of day
Once or twice daily. AM fasted is common; some people inject near the injury site for local effects (e.g. injecting around an injured tendon).
With food or fasted
Doesn't matter for SubQ injection — bypasses the gut. Oral versions exist but absorption is questionable.
How long to cycle
4–8 weeks on, then 2–4 weeks off. Some run it continuously during active injury rehab.
When to get off
No symptom improvement after 4 weeks at full dose → reassess. End each cycle on schedule even if you feel great — long-term human safety is unknown.
Administration
Side effects
Common
- Generally reported as well-tolerated in animal studies
- Injection site irritation
Serious / theoretical
- Unknown long-term human safety profile
Sources: PubMed
Notes
FDA placed BPC-157 on the 503A bulks list as "Category 2" (preliminary safety/efficacy concerns) in 2023.
Further reading & listening
Where the experts go deeper.
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