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Research only·Synthetic heptapeptide (Tuftsin analog)

Selank

Education only. Many compounds discussed are research chemicals not approved for human use in the US. This is not medical advice — consult a licensed physician.

What it is

Russian-developed synthetic peptide based on tuftsin. Used in Russia for generalized anxiety disorder. No FDA approval.

How it works

Modulates GABA, serotonin, and dopamine systems. Animal studies suggest anxiolytic effects without sedation.

What the research says

Russian clinical trials report anxiolytic efficacy. Western RCTs lacking.

Sources: PubMed: Selank

Common dosing ranges

Range
300–900 mcg/day intranasal
Frequency
1–3× daily
Duration
14-day cycles common in Russian protocols

Sources: PubMed

Administration

Nasal

Half-life

Short (minutes plasma)

Side effects

Common

  • Minimal reported

Serious / theoretical

  • Long-term safety unclear

Sources: PubMed