Selank
A 7-amino-acid Russian-developed peptide. Sniffed up the nose for anxiety.
Technically · Synthetic heptapeptide (Tuftsin analog)
In one sentence
A Russian-developed nasal-spray peptide for anxiety — calms without making you sleepy.
— Like a quieter Xanax that you sniff. Approved in Russia, ignored by Western drug regulators.
Half-life
Short (minutes plasma)
In and out of the bloodstream in minutes — used 1-3x daily during a 2-week cycle.
Dosing
1–3× daily
How often you take a dose
Route
Nasal
How it goes into the body
Status
Research
Sold for lab research — not approved for humans
What it is
Russia approved this as an anti-anxiety medication. It's based on tuftsin (a natural immune molecule). You spray it up your nose. Reports say it calms anxiety without the drowsy, foggy side of typical anti-anxiety pills. Western drug regulators haven't evaluated it.
The full technical answer
Russian-developed synthetic peptide based on tuftsin. Used in Russia for generalized anxiety disorder. No FDA approval.
How it works
Selank seems to tap into the same brain systems other anti-anxiety drugs use (GABA, serotonin, dopamine) — but more gently. Think of it as turning down the volume on stress without putting you to sleep.
The full technical answer
Modulates GABA, serotonin, and dopamine systems. Animal studies suggest anxiolytic effects without sedation.
What the research says
Russian clinical trials report anxiolytic efficacy. Western RCTs lacking.
Sources: PubMed: Selank
Common dosing ranges
- Range
- 300–900 mcg/day intranasal
- Frequency
- 1–3× daily
- Duration
- 14-day cycles common in Russian protocols
Sources: PubMed
How to take it
Practical guidance synthesized from clinical protocols, FDA labels, and clinician interviews. Always cross-check with a prescribing physician.
Best time of day
1–3× per day, as needed when anxiety hits. Spray into each nostril, alternating sides per dose.
With food or fasted
Doesn't matter — absorbed through nasal mucosa, bypasses the gut.
How long to cycle
14-day cycles, then 1–2 weeks off. Don't run continuously — efficacy is highest with fresh cycles.
When to get off
End each 2-week cycle on schedule. Long-term continuous use isn't how it was studied.
Administration
Side effects
Further reading & listening
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