HGH Fragment 176-191
The raw fat-burning fragment of HGH (before it was modified into AOD-9604).
Technically · Modified GH fragment (basis for AOD-9604)
In one sentence
The raw, unmodified fragment of HGH supposedly responsible for fat-burning. AOD-9604 is the stable commercial cousin.
— Like ripping out the "burn fat" page of the HGH playbook. Sounds clever, evidence is thin.
Half-life
~30 minutes
About 30 minutes — daily dosing during cycles.
Dosing
Daily, AM fasted
How often you take a dose
Route
SubQ
How it goes into the body
Status
Research
Sold for lab research — not approved for humans
What it is
A small piece of growth hormone — specifically the part that's supposed to be responsible for fat-burning. AOD-9604 is the same piece with a tweak to make it more stable for sale. Marketed for fat loss; the human evidence is thin.
The full technical answer
Unmodified parent fragment of growth hormone (residues 176-191). AOD-9604 is the stabilized commercial version. Marketed for fat loss; clinical data is thin.
How it works
The theory: this slice of HGH triggers fat-burning without spiking IGF-1 (the thing that drives growth and might encourage cancer). Animal data is mixed. Human data is mostly absent.
The full technical answer
Hypothesized to stimulate lipolysis without IGF-1 effects. Animal data is mixed; human data is minimal.
What the research says
Most evidence from rodent models. Human translation of the fat-loss claims has not been validated in published RCTs.
Sources: PubMed: GH fragment 176-191
Common dosing ranges
- Range
- 300–500 mcg/day common
- Frequency
- Daily, AM fasted
- Duration
- 8–12 week cycles
Sources: PubMed
How to take it
Practical guidance synthesized from clinical protocols, FDA labels, and clinician interviews. Always cross-check with a prescribing physician.
Best time of day
AM, fasted.
With food or fasted
Fasted — same logic as the AOD-9604 commercial version.
How long to cycle
8–12 week cycles.
When to get off
Cycle end. Evidence for actual fat-loss benefit is weak — many users abandon after a cycle with no measurable change.
Administration
Side effects
Further reading & listening
Where the experts go deeper.
Curated from the PeptideFacts expert directory — vetted YouTube channels, podcasts, books, and communities. No anecdote-only or supplier-affiliated picks.